I'll prematurely predict The Watchmen (due out in March 09) as a future flop, in the same vein as GI Joe.
After the League of Extraordinary Gentlemen and V for Vendetta, I just can't place any more stock in an Alan Moore adaptation. V for Vendetta was especially bad, perverting the entire aesthetic of Moore's vision to score some cheap present-day political points. Moore was smart enough to call the movie crap--he doesn't seem to mind people making movies of his comics, so long as his name isn't attached to them in any significant way.